Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADU49736.1Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005; KEGG: sna:Snas_6338 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family. (139 aa)    
Predicted Functional Partners:
ADU49737.1
InterPro IPR004360; KEGG: sco:SCO6519 lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Lyase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.
 
     0.957
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.725
ADU49735.1
Diacylglycerol kinase catalytic region; COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: art:Arth_0139 diacylglycerol kinase, catalytic region; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; SPTR: Diacylglycerol kinase, catalytic region; manually curated; PFAM: Diacylglycerol kinase catalytic domain.
       0.578
ADU48607.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018060: IPR018062; KEGG: ach:Achl_1710 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.416
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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