STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49742.1COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR001020: IPR000032: IPR005698; KEGG: cmi:CMM_1505 phosphotransferase system, phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family. (89 aa)    
Predicted Functional Partners:
ADU49741.1
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
 
 
 0.999
ADU49744.1
COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR002173: IPR017583: IPR011611; KEGG: sen:SACE_2273 putative 6-phosphofructokinase; PFAM: PfkB domain protein; PRIAM: 1-phosphofructokinase; SPTR: Putative 6-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family.
 
  
 0.914
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
    0.756
ADU49745.1
Transcriptional regulator, DeoR family; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001969: IPR001034: IPR014036; KEGG: saq:Sare_4851 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: Transcriptional regulator, DeoR family; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain.
 
  
 0.745
tuf
Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
  
 0.726
ADU48973.1
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: fre:Franean1_3256 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family.
 
 
 
 0.614
ADU48974.1
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: fre:Franean1_3256 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family.
 
 
 
 0.606
ADU46635.1
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: sro:Sros_7934 putative LacI-family transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Putative LacI-family transcriptional regulator; manually curated; PFAM: Bacterial regulatory proteins, lacI family; family.
 
 
 
 0.601
ADU50086.1
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: aau:AAur_0084 LacI family transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Regulatory protein, LacI; PFAM: Bacterial regulatory proteins, lacI family; family.
 
 
 
 0.600
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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