STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49743.1PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...] (677 aa)    
Predicted Functional Partners:
ADU49744.1
COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR002173: IPR017583: IPR011611; KEGG: sen:SACE_2273 putative 6-phosphofructokinase; PFAM: PfkB domain protein; PRIAM: 1-phosphofructokinase; SPTR: Putative 6-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family.
 
 
 0.999
ADU49742.1
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR001020: IPR000032: IPR005698; KEGG: cmi:CMM_1505 phosphotransferase system, phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
 
 
 0.997
ADU49745.1
Transcriptional regulator, DeoR family; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001969: IPR001034: IPR014036; KEGG: saq:Sare_4851 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: Transcriptional regulator, DeoR family; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain.
 
  
 0.994
ADU49741.1
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.983
ADU49748.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.979
ADU48602.1
COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR000669: IPR013131: IPR013118; KEGG: kfl:Kfla_1360 mannitol dehydrogenase domain protein; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: Mannitol dehydrogenase domain protein; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
  
 
 0.976
ADU49196.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611: IPR002173; KEGG: tpr:Tpau_0525 PfkB domain protein; PFAM: PfkB domain protein; SPTR: Putative uncharacterized protein; PFAM: pfkB family carbohydrate kinase.
    
 0.946
ADU48194.1
Hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.851
ADU47641.1
Ketose-bisphosphate aldolase class-II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: ach:Achl_0507 ketose-bisphosphate aldolase class-II; PFAM: ketose-bisphosphate aldolase class-II; SPTR: Ketose-bisphosphate aldolase class-II; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases.
 
  
 0.783
ADU48970.1
COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR000669: IPR013131: IPR013118; KEGG: fre:Franean1_3198 mannitol dehydrogenase domain-containing protein; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: Mannitol dehydrogenase domain protein; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
  
  
 0.777
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.