STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49744.1COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR002173: IPR017583: IPR011611; KEGG: sen:SACE_2273 putative 6-phosphofructokinase; PFAM: PfkB domain protein; PRIAM: 1-phosphofructokinase; SPTR: Putative 6-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family. (315 aa)    
Predicted Functional Partners:
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
 
 
 0.999
ADU49745.1
Transcriptional regulator, DeoR family; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001969: IPR001034: IPR014036; KEGG: saq:Sare_4851 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: Transcriptional regulator, DeoR family; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain.
 
  
 0.991
ADU49741.1
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.959
ADU49748.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.950
pfkA
Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
  
 0.942
ADU49742.1
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR001020: IPR000032: IPR005698; KEGG: cmi:CMM_1505 phosphotransferase system, phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
 
  
 0.914
ADU49195.1
Fructose-1,6-bisphosphatase, class II; COGs: COG1494 Fructose-1 6-bisphosphatase/sedoheptulose 1 7-bisphosphatase and related protein; InterPro IPR004464; KEGG: kfl:Kfla_5587 fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; PRIAM: Fructose-bisphosphatase; SPTR: Putative fructose-1,6-bisphosphatase II; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II.
     
 0.903
ADU50085.1
Broad-specificity cellobiase; COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR001360: IPR017736; KEGG: jde:Jden_1879 beta-galactosidase; PFAM: glycoside hydrolase family 1; PRIAM: Beta-glucosidase; SPTR: Putative cellobiose hydrolase; TIGRFAM: beta-galactosidase; PFAM: Glycosyl hydrolase family 1; TIGRFAM: beta-galactosidase.
 
  
 0.841
ADU47879.1
COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR011860: IPR003500; KEGG: kse:Ksed_09040 ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; SPTR: Ribose 5-phosphate isomerase; TIGRFAM: ribose 5-phosphate isomerase; sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase; sugar-phosphate isomerases, RpiB/LacA/LacB family.
  
  
 0.816
ADU48274.1
Peptidase M50; COGs: COG1994 Zn-dependent protease; InterPro IPR000644: IPR008915; KEGG: xce:Xcel_1483 peptidase M50; PFAM: peptidase M50; SPTR: Putative peptidase; PFAM: Peptidase family M50.
  
    0.771
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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