STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49764.1COGs: COG3629 DNA-binding transcriptional activator of the SARP family; InterProIPR019775: IPR019782: IPR017986: IPR001680: IPR 001867: IPR005158; KEGG: nml:Namu_2911 transcriptional regulator, SARP family; PFAM: transcriptional activator domain; transcriptional regulator domain-containing protein; SPTR: Transcriptional regulator, SARP family; PFAM: Bacterial transcriptional activator domain; Transcriptional regulatory protein, C terminal. (1399 aa)    
Predicted Functional Partners:
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 0.923
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.884
ADU47546.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG2303 Choline dehydrogenase and related flavoprotein; InterPro IPR013027; KEGG: rer:RER_19350 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative cholesterol oxidase; PFAM: GMC oxidoreductase.
  
 
 0.867
ADU48265.1
KEGG: sen:SACE_2204 phosphatidylinositol 3-and 4-kinase, catalytic; SPTR: Phosphatidylinositol 3-and 4-kinase, catalytic; PFAM: Phosphatidylinositol 3- and 4-kinase; TIGRFAM: conserved hypothetical protein.
    
 0.861
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 0.827
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.824
ADU49125.1
Hypothetical protein; InterPro IPR017909: IPR006311; KEGG: kse:Ksed_18940 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.813
ADU48668.1
Helicase c2; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR014001: IPR006555: IPR014013; KEGG: kse:Ksed_17400 DNA helicase, Rad3; SMART: helicase c2; DEAD-like helicase; SPTR: Putative ATP-dependent helicase; PFAM: DEAD/DEAH box helicase.
   
  0.786
ADU49390.1
KEGG: pjd:Pjdr2_2870 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 0.784
ADU47191.1
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: kra:Krad_0611 histone deacetylase superfamily; PFAM: histone deacetylase superfamily; PRIAM: Histone deacetylase; SPTR: Putative acetoin utilization protein; PFAM: Histone deacetylase domain.
   
 0.780
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.