Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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ADU49788.1Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. (439 aa)    
Predicted Functional Partners:
ADU49787.1
InterPro IPR004193; KEGG: nca:Noca_2674 hypothetical protein; PFAM: glycoside hydrolase family 13 domain protein; SPTR: Putative uncharacterized protein; PFAM: PhoD-like phosphatase.
 
     0.691
ADU49918.1
InterPro IPR009597; KEGG: ske:Sked_35130 protein of unknown function (DUF1206); PFAM: protein of unknown function DUF1206; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1206).
  
     0.601
ADU49789.1
Transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR000485: IPR019888: IPR019887; KEGG: nca:Noca_3944 AsnC family transcriptional regulator; PFAM: Transcription regulator AsnC-type-like; SMART: Transcription regulator AsnC-type; SPTR: Possible transcriptional regulatory protein (Probably lrp/asnc-family protein); PFAM: IclR helix-turn-helix domain; AsnC family.
       0.570
ADU47003.1
F420-dependent oxidoreductase, G6PDH family; COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR019945; KEGG: mgi:Mflv_3722 putative dehydrogenase protein; SPTR: Putative dehydrogenase protein; TIGRFAM: F420-dependent oxidoreductase, G6PDH family; PFAM: Luciferase-like monooxygenase; TIGRFAM: F420-dependent oxidoreductase, G6PDH family.
  
     0.521
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
 
 
 
 0.448
ADU49790.1
COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: nca:Noca_3943 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme.
  
    0.432
ADU47933.1
InterPro IPR011600; KEGG: npu:Npun_R3338 peptidase C14, caspase catalytic subunit P20; PFAM: peptidase C14 caspase catalytic subunit p20; SPTR: Putative uncharacterized protein; PFAM: Caspase domain.
  
     0.430
ADU48268.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.422
ADU48405.1
Hypothetical protein; InterPro IPR013434; KEGG: kfl:Kfla_3574 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Putative transmembrane protein (PGPGW); TIGRFAM: conserved hypothetical protein TIGR02611.
 
 
 
 0.410
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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