| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU46986.1 | ADU49309.1 | Intca_0438 | Intca_2808 | PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...] | Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789: IPR000103: IPR013027; KEGG: rer:RER_40230 two-component system thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Response regulator receiver domain. | 0.999 |
| ADU46986.1 | ADU49788.1 | Intca_0438 | Intca_3305 | PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...] | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | 0.460 |
| ADU47003.1 | ADU49788.1 | Intca_0455 | Intca_3305 | F420-dependent oxidoreductase, G6PDH family; COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR019945; KEGG: mgi:Mflv_3722 putative dehydrogenase protein; SPTR: Putative dehydrogenase protein; TIGRFAM: F420-dependent oxidoreductase, G6PDH family; PFAM: Luciferase-like monooxygenase; TIGRFAM: F420-dependent oxidoreductase, G6PDH family. | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | 0.521 |
| ADU47933.1 | ADU49788.1 | Intca_1417 | Intca_3305 | InterPro IPR011600; KEGG: npu:Npun_R3338 peptidase C14, caspase catalytic subunit P20; PFAM: peptidase C14 caspase catalytic subunit p20; SPTR: Putative uncharacterized protein; PFAM: Caspase domain. | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | 0.430 |
| ADU49309.1 | ADU46986.1 | Intca_2808 | Intca_0438 | Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789: IPR000103: IPR013027; KEGG: rer:RER_40230 two-component system thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Response regulator receiver domain. | PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...] | 0.999 |
| ADU49309.1 | ADU49788.1 | Intca_2808 | Intca_3305 | Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789: IPR000103: IPR013027; KEGG: rer:RER_40230 two-component system thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Response regulator receiver domain. | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | 0.414 |
| ADU49309.1 | ADU49790.1 | Intca_2808 | Intca_3307 | Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789: IPR000103: IPR013027; KEGG: rer:RER_40230 two-component system thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Response regulator receiver domain. | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: nca:Noca_3943 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.906 |
| ADU49787.1 | ADU49788.1 | Intca_3304 | Intca_3305 | InterPro IPR004193; KEGG: nca:Noca_2674 hypothetical protein; PFAM: glycoside hydrolase family 13 domain protein; SPTR: Putative uncharacterized protein; PFAM: PhoD-like phosphatase. | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | 0.691 |
| ADU49787.1 | ADU49789.1 | Intca_3304 | Intca_3306 | InterPro IPR004193; KEGG: nca:Noca_2674 hypothetical protein; PFAM: glycoside hydrolase family 13 domain protein; SPTR: Putative uncharacterized protein; PFAM: PhoD-like phosphatase. | Transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR000485: IPR019888: IPR019887; KEGG: nca:Noca_3944 AsnC family transcriptional regulator; PFAM: Transcription regulator AsnC-type-like; SMART: Transcription regulator AsnC-type; SPTR: Possible transcriptional regulatory protein (Probably lrp/asnc-family protein); PFAM: IclR helix-turn-helix domain; AsnC family. | 0.483 |
| ADU49788.1 | ADU46986.1 | Intca_3305 | Intca_0438 | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...] | 0.460 |
| ADU49788.1 | ADU47003.1 | Intca_3305 | Intca_0455 | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | F420-dependent oxidoreductase, G6PDH family; COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR019945; KEGG: mgi:Mflv_3722 putative dehydrogenase protein; SPTR: Putative dehydrogenase protein; TIGRFAM: F420-dependent oxidoreductase, G6PDH family; PFAM: Luciferase-like monooxygenase; TIGRFAM: F420-dependent oxidoreductase, G6PDH family. | 0.521 |
| ADU49788.1 | ADU47933.1 | Intca_3305 | Intca_1417 | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | InterPro IPR011600; KEGG: npu:Npun_R3338 peptidase C14, caspase catalytic subunit P20; PFAM: peptidase C14 caspase catalytic subunit p20; SPTR: Putative uncharacterized protein; PFAM: Caspase domain. | 0.430 |
| ADU49788.1 | ADU49309.1 | Intca_3305 | Intca_2808 | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789: IPR000103: IPR013027; KEGG: rer:RER_40230 two-component system thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Response regulator receiver domain. | 0.414 |
| ADU49788.1 | ADU49787.1 | Intca_3305 | Intca_3304 | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | InterPro IPR004193; KEGG: nca:Noca_2674 hypothetical protein; PFAM: glycoside hydrolase family 13 domain protein; SPTR: Putative uncharacterized protein; PFAM: PhoD-like phosphatase. | 0.691 |
| ADU49788.1 | ADU49789.1 | Intca_3305 | Intca_3306 | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | Transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR000485: IPR019888: IPR019887; KEGG: nca:Noca_3944 AsnC family transcriptional regulator; PFAM: Transcription regulator AsnC-type-like; SMART: Transcription regulator AsnC-type; SPTR: Possible transcriptional regulatory protein (Probably lrp/asnc-family protein); PFAM: IclR helix-turn-helix domain; AsnC family. | 0.570 |
| ADU49788.1 | ADU49790.1 | Intca_3305 | Intca_3307 | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: nca:Noca_3943 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.425 |
| ADU49788.1 | ADU49918.1 | Intca_3305 | Intca_3439 | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | InterPro IPR009597; KEGG: ske:Sked_35130 protein of unknown function (DUF1206); PFAM: protein of unknown function DUF1206; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1206). | 0.601 |
| ADU49789.1 | ADU49787.1 | Intca_3306 | Intca_3304 | Transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR000485: IPR019888: IPR019887; KEGG: nca:Noca_3944 AsnC family transcriptional regulator; PFAM: Transcription regulator AsnC-type-like; SMART: Transcription regulator AsnC-type; SPTR: Possible transcriptional regulatory protein (Probably lrp/asnc-family protein); PFAM: IclR helix-turn-helix domain; AsnC family. | InterPro IPR004193; KEGG: nca:Noca_2674 hypothetical protein; PFAM: glycoside hydrolase family 13 domain protein; SPTR: Putative uncharacterized protein; PFAM: PhoD-like phosphatase. | 0.483 |
| ADU49789.1 | ADU49788.1 | Intca_3306 | Intca_3305 | Transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR000485: IPR019888: IPR019887; KEGG: nca:Noca_3944 AsnC family transcriptional regulator; PFAM: Transcription regulator AsnC-type-like; SMART: Transcription regulator AsnC-type; SPTR: Possible transcriptional regulatory protein (Probably lrp/asnc-family protein); PFAM: IclR helix-turn-helix domain; AsnC family. | Sodium/proton antiporter, CPA1 family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: nca:Noca_3759 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family; TC 2.A.36. | 0.570 |
| ADU49789.1 | ADU49790.1 | Intca_3306 | Intca_3307 | Transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR000485: IPR019888: IPR019887; KEGG: nca:Noca_3944 AsnC family transcriptional regulator; PFAM: Transcription regulator AsnC-type-like; SMART: Transcription regulator AsnC-type; SPTR: Possible transcriptional regulatory protein (Probably lrp/asnc-family protein); PFAM: IclR helix-turn-helix domain; AsnC family. | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: nca:Noca_3943 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.577 |