Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ADU49810.1COGs: COG4721 membrane protein; InterPro IPR017195; KEGG: kra:Krad_4237 ABC transporter, permease protein; PFAM: ABC-type thiamin-related transport system, permease component 1, predicted; SPTR: ABC transporter, permease protein; PFAM: ABC-type cobalt transport system, permease component. (211 aa)    
Predicted Functional Partners:
ADU49809.1
ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR017871: IPR003439: IPR003593: IPR003339; KEGG: bfa:Bfae_11750 ATPase component of various ABC-type transport systems with duplicated ATPase domain; PFAM: ABC transporter related; cobalt transport protein; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter; Cobalt transport protein.
 
  
 0.984
ADU49807.1
Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR001345: IPR013078; KEGG: aau:AAur_3898 phosphoglycerate mutase family protein; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase family protein; PFAM: Phosphoglycerate mutase family.
       0.663
ADU49808.1
Hypothetical protein; KEGG: lbz:LbrM15_V2.1240 cysteine peptidase, Clan CA, family C19; SPTR: Putative uncharacterized protein.
       0.663
ADU49806.1
KEGG: saq:Sare_3577 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2029).
       0.662
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
   
  
 0.549
ADU47915.1
COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399: IPR013749; KEGG: nca:Noca_3401 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Phosphomethylpyrimidine kinase; SPTR: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase.
  
    0.542
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
    0.523
ADU47918.1
Thiamine biosynthesis protein ThiS; InterPro IPR010035: IPR003749; KEGG: mmi:MMAR_0719 thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS.
  
    0.517
ADU47458.1
Septum formation initiator; InterPro IPR007060; KEGG: kra:Krad_1074 septum formation initiator; PFAM: Septum formation initiator; SPTR: Septum formation initiator; PFAM: Septum formation initiator.
  
     0.483
ADU48520.1
ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439: IPR003593: IPR017871; KEGG: kfl:Kfla_2709 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter.
  
  
 0.476
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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