STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49823.1COGs: COG2986 Histidine ammonia-lyase; InterPro IPR001106: IPR005921; KEGG: nfa:nfa12280 histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; PRIAM: Histidine ammonia-lyase; SPTR: Histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase. (522 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.999
hutI
COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR005920: IPR006680; KEGG: bcv:Bcav_1839 imidazolonepropionase; PFAM: amidohydrolase; PRIAM: Imidazolonepropionase; SPTR: Putative chlorohydrolase; TIGRFAM: imidazolonepropionase; PFAM: Amidohydrolase family; TIGRFAM: imidazolonepropionase.
 
  
 0.984
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.924
ADU46735.1
Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: mbt:JTY_0076 hypothetical protein; PFAM: amidohydrolase; SPTR: Putative uncharacterized protein Mb0076; PFAM: Amidohydrolase family.
  
  
 0.785
ADU48804.1
Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: sma:SAV_6403 hypothetical protein; PFAM: amidohydrolase; SPTR: Putative uncharacterized protein; PFAM: Amidohydrolase family.
  
  
 0.785
ADU49824.1
Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: krh:KRH_22930 IclR family transcriptional regulator; PFAM: regulatory protein IclR; Transcriptional regulator IclR; SMART: regulatory protein IclR; SPTR: Transcriptional regulator, IclR family protein; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator.
 
   
 0.699
ADU49818.1
Formiminoglutamate deiminase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR010252: IPR006680; KEGG: nml:Namu_0039 formiminoglutamate deiminase; PFAM: amidohydrolase; SPTR: Formiminoglutamate deiminase; TIGRFAM: formiminoglutamate deiminase; PFAM: Amidohydrolase family; TIGRFAM: formiminoglutamate deiminase.
 
  
 0.663
gcvP
Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
  
 0.591
gcvP-2
Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
  
 0.591
ADU46698.1
Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 000022: IPR011761: IPR011764: IPR011763; KEGG: kfl:Kfla_3307 carbamoyl-phosphate synthase L chain ATP-binding protein; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; carboxyl transferase; SPTR: Carbamoyl-phosphate synthase L chain ATP-binding protein; PFAM: Car [...]
  
 
 0.444
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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