STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49830.1Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: lxx:Lxx07500 two-component system, regulatory protein; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: LuxR family DNA-binding response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (209 aa)    
Predicted Functional Partners:
ADU49829.1
COGs: COG4585 Signal transduction histidine kinase; InterProIPR005467: IPR004358: IPR003594: IPR017205: IPR 011712; KEGG: sco:SCO1369 two component system histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: Probable two component system histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.969
ADU49498.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594: IPR005467: IPR013767: IPR011712; KEGG: nca:Noca_2942 ATPase domain-containing protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: ATP-binding region, ATPase domain protein domain protein; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.862
ADU48392.1
COGs: COG3850 Signal transduction histidine kinase nitrate/nitrite-specific; InterPro IPR011712: IPR003594: IPR005467; KEGG: ttr:Tter_2549 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: GAF sensor signal transduction histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.817
ADU49815.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003018: IPR011712: IPR003594; KEGG: saq:Sare_1529 GAF sensor signal transduction histidine kinase; PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; SPTR: GAF sensor signal transduction histidine kinase; PFAM: Histidine kinase; GAF domain.
 
 
 0.750
ADU47489.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712: IPR003594; KEGG: pak:HMPREF0675_3336 histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SPTR: Putative two-component sensor kinase; PFAM: Histidine kinase.
 
 
 0.635
ADU49828.1
KEGG: nml:Namu_3002 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.563
ADU49831.1
Protein of unknown function DUF2587; InterPro IPR019695; KEGG: kra:Krad_0259 hypothetical protein; PFAM: Protein of unknown function DUF2587; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2587).
       0.498
ADU49832.1
Metallophosphoesterase; InterPro IPR004843; KEGG: bfa:Bfae_11330 predicted phosphohydrolase; PFAM: metallophosphoesterase; SPTR: Putative integral membrane protein; PFAM: Calcineurin-like phosphoesterase.
       0.462
ADU47498.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR007168: IPR003594; KEGG: art:Arth_2999 putative signal transduction histidine kinase; PFAM: PspC domain protein; ATP-binding region ATPase domain protein; SPTR: Putative signal transduction histidine kinase; PFAM: PspC domain.
  
 
 0.455
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
  
 
 0.450
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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