STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49851.1Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: kfl:Kfla_0582 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family; Belongs to the Fur family. (178 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.627
ADU49849.1
KEGG: kse:Ksed_04980 predicted hydrolase or acyltransferase of alpha/beta superfamily; SPTR: Predicted hydrolase or acyltransferase of alpha/beta superfamily.
       0.550
ADU49850.1
L-threonine 3-dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328: IPR013154: IPR013149; KEGG: nca:Noca_3757 L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: L-threonine 3-dehydrogenase; 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase.
       0.548
ADU47771.1
COGs: COG1832 CoA-binding protein; KEGG: bcv:Bcav_1164 CoA-binding domain protein; SPTR: Putative uncharacterized protein.
  
    0.525
ADU49887.1
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: rha:RHA1_ro04308 Fe(3+) uptake regulator; PFAM: ferric-uptake regulator; SPTR: Fe(3+) uptake regulator; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
  
     0.473
ADU48632.1
ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: gob:Gobs_1601 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC-type Mn/Zn transport systems ATPase component; PFAM: ABC transporter.
  
  
 0.461
sigA
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.452
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
 
  
 0.439
ADU46683.1
COGs: COG2345 transcriptional regulator protein; KEGG: mgi:Mflv_3487 putative transcriptional regulator; SPTR: Transcriptional regulator.
  
    0.430
ADU46936.1
COGs: COG2345 transcriptional regulator protein; KEGG: nca:Noca_2106 transcriptional regulator; SPTR: Transcriptional regulator; PFAM: IclR helix-turn-helix domain.
  
    0.430
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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