STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Cooccurrence
Coexpression
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[Homology]
Score
ADU49857.1SNF2-related protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterProIPR007527: IPR014021: IPR001650: IPR014001: IPR 000330; KEGG: pfr:PFREUD_00710 helicase (SNF2-related protein); PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: SNF2-like; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. (1147 aa)    
Predicted Functional Partners:
ADU49059.1
ATP-dependent DNA helicase, Rep family; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR002121: IPR014016: IPR014017: IPR000212; KEGG: kra:Krad_1179 UvrD/REP helicase; PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; SPTR: Putative ATP-dependent DNA helicase; manually curated; PFAM: HRDC domain; UvrD/REP helicase.
  
 
 0.853
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.721
ADU49909.1
COGs: COG4279 conserved hypothetical protein; InterPro IPR007527; KEGG: mtb:TBMG_01880 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: SWIM zinc finger.
    0.653
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.649
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.644
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.640
ADU46564.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.622
ADU49858.1
Luciferase-like, subgroup; COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048; KEGG: nca:Noca_3005 luciferase family protein; PFAM: Luciferase-like, subgroup; SPTR: Luciferase family protein; PFAM: Luciferase-like monooxygenase.
       0.616
ADU49859.1
Protein of unknown function DUF1697; COGs: COG3797 conserved hypothetical protein; InterPro IPR012545; KEGG: nca:Noca_1298 hypothetical protein; PFAM: protein of unknown function DUF1697; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1697).
       0.565
ADU47191.1
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: kra:Krad_0611 histone deacetylase superfamily; PFAM: histone deacetylase superfamily; PRIAM: Histone deacetylase; SPTR: Putative acetoin utilization protein; PFAM: Histone deacetylase domain.
   
 0.558
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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