STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49887.1Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: rha:RHA1_ro04308 Fe(3+) uptake regulator; PFAM: ferric-uptake regulator; SPTR: Fe(3+) uptake regulator; PFAM: Ferric uptake regulator family; Belongs to the Fur family. (147 aa)    
Predicted Functional Partners:
ADU49888.1
Catalase; COGs: COG0753 Catalase; InterPro IPR018028: IPR010582: IPR011614: IPR002226; KEGG: sco:SCO0379 catalase; PFAM: Catalase related subgroup; Catalase domain protein; PRIAM: Catalase; SPTR: Catalase; PFAM: Catalase; Catalase-related immune-responsive; Belongs to the catalase family.
    
 0.896
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
 0.754
ADU48634.1
Zinc uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: mmi:MMAR_3669 zinc uptake regulation protein Zur; PFAM: ferric-uptake regulator; SPTR: Zinc uptake regulation protein Zur; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
  
   
0.590
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.561
ADU47299.1
Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001808: IPR001367: IPR007167; KEGG: kse:Ksed_24030 Mn-dependent transcriptional regulator; PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor; regulatory protein Crp; SPTR: Iron-dependent repressor, DxtR metalloregulatory family protein; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.
  
  
 0.540
ADU47771.1
COGs: COG1832 CoA-binding protein; KEGG: bcv:Bcav_1164 CoA-binding domain protein; SPTR: Putative uncharacterized protein.
  
    0.523
sigA
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.482
ADU49851.1
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: kfl:Kfla_0582 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
  
     0.473
ADU46683.1
COGs: COG2345 transcriptional regulator protein; KEGG: mgi:Mflv_3487 putative transcriptional regulator; SPTR: Transcriptional regulator.
  
    0.452
ADU46936.1
COGs: COG2345 transcriptional regulator protein; KEGG: nca:Noca_2106 transcriptional regulator; SPTR: Transcriptional regulator; PFAM: IclR helix-turn-helix domain.
  
    0.452
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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