STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (502 aa)    
Predicted Functional Partners:
ADU49899.1
COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076: IPR000447; KEGG: sen:SACE_6515 glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: Glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 0.998
ADU47507.1
COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076: IPR000447; KEGG: tpr:Tpau_1956 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 0.993
arc
AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 0.929
plsY
Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.925
ADU48077.1
HAD-superfamily hydrolase, subfamily IIA; COGs: COG0647 sugar phosphatase of the HAD superfamily; InterPro IPR005834: IPR006357; KEGG: sro:Sros_6062 sugar phosphatase of the HAD superfamily-like protein; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Sugar phosphatase of the HAD superfamily-like protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase Superfamily Class (subfamily) IIA.
  
 
 0.911
prcB
Proteasome endopeptidase complex, beta component; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
   
 0.869
prcA
20S proteasome A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
   
 0.869
ADU47388.1
MIP family channel protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425: IPR012269; KEGG: fpl:Ferp_1369 MIP family channel protein; PFAM: major intrinsic protein; SPTR: MIP family channel protein; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.813
ADU47652.1
MIP family channel protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425: IPR012269; KEGG: kse:Ksed_02220 MIP family channel protein; PFAM: major intrinsic protein; SPTR: Aquaporin Z; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.813
ADU49349.1
MIP family channel protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425: IPR012269; KEGG: mtp:Mthe_1139 MIP family channel protein; PFAM: major intrinsic protein; SPTR: MIP family channel proteins; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.813
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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