STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49932.1COGs: COG0648 Endonuclease IV; InterPro IPR012307: IPR001719: IPR018246; KEGG: nca:Noca_4666 endonuclease IV; PFAM: Xylose isomerase domain-containing protein TIM barrel; SMART: AP endonuclease family 2; SPTR: Endonuclease IV; manually curated; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: apurinic endonuclease (APN1). (265 aa)    
Predicted Functional Partners:
ADU49760.1
COGs: COG0708 Exonuclease III; InterPro IPR004808: IPR000097: IPR005135; KEGG: tfu:Tfu_0258 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth).
    
 
 0.836
ADU47714.1
Exodeoxyribonuclease III Xth; COGs: COG0708 Exonuclease III; InterPro IPR005135: IPR004808; KEGG: cfl:Cfla_2498 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth).
    
 
 0.828
ADU48120.1
COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR018089: IPR001754: IPR011995; KEGG: kra:Krad_3000 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily.
     
 0.674
ADU47339.1
COGs: COG2875 Precorrin-4 methylase; InterPro IPR000878: IPR003043; KEGG: tfu:Tfu_0315 precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Putative methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.
      
 0.668
ADU47744.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027: IPR004099: IPR000815; KEGG: nca:Noca_3517 flavoprotein disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
      
 0.665
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.619
ADU47106.1
Dimethylargininase; COGs: COG1834 N-Dimethylarginine dimethylaminohydrolase; InterPro IPR003198; KEGG: kfl:Kfla_3423 dimethylargininase; PFAM: amidinotransferase; PRIAM: Dimethylargininase; SPTR: Dimethylarginine dimethylaminohydrolase; PFAM: Amidinotransferase.
     
 0.607
ADU48489.1
DNA polymerase III, epsilon subunit; COGs: COG0322 Nuclease subunit of the excinuclease complex; InterPro IPR013520: IPR000305: IPR006055: IPR006054; KEGG: kra:Krad_3247 hypothetical protein; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; GIY-YIG catalytic domain; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family.
 
   
 0.591
ADU47479.1
HhH-GPD family protein; InterPro IPR003265: IPR017658; KEGG: sgr:SGR_3531 hypothetical protein; PFAM: HhH-GPD family protein; SPTR: HhH-GPD family protein; TIGRFAM: HhH-GPD family protein; PFAM: HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: uncharacterized HhH-GPD family protein.
 
 
 0.569
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.528
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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