Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU49934.1Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; COGs: COG3573 oxidoreductase; InterPro IPR014614: IPR003953; KEGG: nca:Noca_1140 putative FAD-binding dehydrogenase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: FAD binding domain. (548 aa)    
Predicted Functional Partners:
ADU49935.1
HNH nuclease; InterPro IPR003615; KEGG: rop:ROP_20630 hypothetical protein; SMART: HNH nuclease; SPTR: Putative uncharacterized protein.
       0.550
ADU49933.1
ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525: IPR000412; KEGG: mjl:Mjls_4638 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter; manually curated; PFAM: ABC-2 type transporter.
       0.496
ADU49936.1
COGs: COG3345 Alpha-galactosidase; InterPro IPR002252: IPR000111; KEGG: kfl:Kfla_1749 glycoside hydrolase clan GH-D; PFAM: glycoside hydrolase clan GH-D; PRIAM: Alpha-galactosidase; SPTR: Glycoside hydrolase clan GH-D; PFAM: Melibiase.
       0.470
ADU49937.1
COGs: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; InterPro IPR001126: IPR017963; KEGG: art:Arth_2021 DNA polymerase IV; PFAM: UMUC domain protein DNA-repair protein; PRIAM: DNA-directed DNA polymerase; SPTR: DNA-directed DNA polymerase; PFAM: impB/mucB/samB family C-terminal; impB/mucB/samB family.
       0.420
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (30%) [HD]