STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU49954.1COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122; KEGG: bcv:Bcav_1028 uracil-DNA glycosylase superfamily; PFAM: Uracil-DNA glycosylase superfamily; SPTR: Putative uncharacterized protein; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4. (280 aa)    
Predicted Functional Partners:
ADU49953.1
Regulatory protein TetR; InterPro IPR001647; KEGG: nca:Noca_2173 regulatory protein, TetR; PFAM: regulatory protein TetR; SPTR: Regulatory protein, TetR; PFAM: Bacterial regulatory proteins, tetR family.
       0.773
ADU49955.1
COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: phe:Phep_0285 O-methyltransferase; PFAM: O-methyltransferase family 3; SPTR: O-methyltransferase; PFAM: O-methyltransferase.
       0.565
ADU47532.1
Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: sgr:SGR_2781 hypothetical protein; PFAM: peptidase M22 glycoprotease; SPTR: Putative uncharacterized protein; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ.
  
    0.549
ADU49952.1
MmpL domain-containing protein; COGs: COG2409 drug exporter of the RND superfamily; InterPro IPR000731; KEGG: nca:Noca_2172 MmpL domain-containing protein; SPTR: MMPL domain protein; manually curated; PFAM: MMPL family.
       0.527
gpmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
    0.500
mutM
DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
     
 0.470
ADU47942.1
ComEC/Rec2-related protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477; KEGG: kra:Krad_3434 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Putative integral membrane protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
     
 0.467
ADU49904.1
ATP dependent helicase, Lhr family; COGs: COG1201 Lhr-like helicase; InterProIPR011545: IPR001650: IPR013701: IPR014021: IPR 014001; KEGG: kra:Krad_1489 DEAD/H associated domain protein; PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Putative ATP-dependent DNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase.
 
     0.452
ADU49201.1
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
       0.437
ADU47802.1
Hypothetical protein; COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; KEGG: nca:Noca_2841 hypothetical protein; SPTR: Putative uncharacterized protein.
 
   
 0.417
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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