STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
idiIsopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (212 aa)    
Predicted Functional Partners:
ADU48471.1
Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: kra:Krad_3227 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Putative polyprenyl synthase / dimethylallyltranstransferase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.965
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.951
ADU47521.1
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
 
 0.915
ADU49996.1
FAD dependent oxidoreductase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR006076: IPR003042; KEGG: mpa:MAP2644 hypothetical protein; PFAM: FAD dependent oxidoreductase; SPTR: Monooxygenase; PFAM: FAD binding domain.
  
  
 0.831
ADU49998.1
Chalcone and stilbene synthase domain protein; COGs: COG3424 naringenin-chalcone synthase; InterPro IPR011141: IPR001099: IPR012328; KEGG: kse:Ksed_00500 predicted naringenin-chalcone synthase; PFAM: chalcone and stilbene synthase domain protein; SPTR: Chalcone and stilbene synthases domain-containing protein; PFAM: FAE1/Type III polyketide synthase-like protein; Chalcone and stilbene synthases, C-terminal domain.
 
     0.802
ADU49997.1
Isoprenylcysteine carboxyl methyltransferase; COGs: COG1755 conserved hypothetical protein; InterPro IPR007269; KEGG: kfl:Kfla_2548 isoprenylcysteine carboxyl methyltransferase; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: Isoprenylcysteine carboxyl methyltransferase; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family.
       0.784
ADU49999.1
InterPro IPR000537; KEGG: nml:Namu_5114 UbiA prenyltransferase; PFAM: UbiA prenyltransferase; SPTR: Putative integral membrane protein; PFAM: UbiA prenyltransferase family.
 
  
 0.764
ispE
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
     
 0.588
ADU47244.1
Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: kse:Ksed_21410 geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; SPTR: Putative polyprenyl diphosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
  
 0.563
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.543
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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