STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADU50000.1COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR002755; KEGG: kse:Ksed_15620 DNA polymerase LigD, polymerase domain; PFAM: DNA primase small subunit; SPTR: DNA ligase; TIGRFAM: DNA polymerase LigD, polymerase domain. (320 aa)    
Predicted Functional Partners:
ADU50001.1
COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR012309; KEGG: nml:Namu_0826 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: DNA ligase; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region.
   
 0.987
ADU47171.1
DNA polymerase LigD, ligase domain protein; COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR014146: IPR016059; KEGG: cfl:Cfla_1903 DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase; SPTR: DNA ligase; TIGRFAM: DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domain.
   
 0.978
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.882
ADU49698.1
COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR000977: IPR012309; KEGG: nca:Noca_2845 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; PRIAM: DNA ligase (ATP); SPTR: Probable DNA ligase; TIGRFAM: DNA ligase I, ATP-dependent Dnl1; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA ligase I, ATP-dependent (dnl1); Belongs to the ATP-dependent DNA ligase family.
   
 0.716
ADU49999.1
InterPro IPR000537; KEGG: nml:Namu_5114 UbiA prenyltransferase; PFAM: UbiA prenyltransferase; SPTR: Putative integral membrane protein; PFAM: UbiA prenyltransferase family.
       0.646
ADU50077.1
Protein of unknown function DUF2277; COGs: COG5552 conserved hypothetical protein; InterPro IPR018735; KEGG: ach:Achl_3874 hypothetical protein; PFAM: Protein of unknown function DUF2277; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2277).
  
     0.569
ADU49998.1
Chalcone and stilbene synthase domain protein; COGs: COG3424 naringenin-chalcone synthase; InterPro IPR011141: IPR001099: IPR012328; KEGG: kse:Ksed_00500 predicted naringenin-chalcone synthase; PFAM: chalcone and stilbene synthase domain protein; SPTR: Chalcone and stilbene synthases domain-containing protein; PFAM: FAE1/Type III polyketide synthase-like protein; Chalcone and stilbene synthases, C-terminal domain.
       0.473
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
       0.470
ADU49996.1
FAD dependent oxidoreductase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR006076: IPR003042; KEGG: mpa:MAP2644 hypothetical protein; PFAM: FAD dependent oxidoreductase; SPTR: Monooxygenase; PFAM: FAD binding domain.
       0.470
ADU49997.1
Isoprenylcysteine carboxyl methyltransferase; COGs: COG1755 conserved hypothetical protein; InterPro IPR007269; KEGG: kfl:Kfla_2548 isoprenylcysteine carboxyl methyltransferase; PFAM: Isoprenylcysteine carboxyl methyltransferase; SPTR: Isoprenylcysteine carboxyl methyltransferase; PFAM: Isoprenylcysteine carboxyl methyltransferase (ICMT) family.
       0.470
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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