Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADU50026.1COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR020845; KEGG: gob:Gobs_4160 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative acyl-CoA synthetase, long-chain fatty acid:CoA ligase; PFAM: AMP-binding enzyme. (502 aa)    
Predicted Functional Partners:
ADU47762.1
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022: IPR011762: IPR011763: IPR000438; KEGG: kfl:Kfla_1439 carboxyl transferase; PFAM: carboxyl transferase; SPTR: Propionyl-CoA carboxylase complex B subunit; PFAM: Carboxyl transferase domain.
  
 0.840
ADU47746.1
Biotin carboxyl carrier protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 001882: IPR011761: IPR011764; KEGG: kse:Ksed_08190 acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Putative acyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-te [...]
  
 
 0.835
ADU48729.1
AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845: IPR018294: IPR000873; KEGG: kfl:Kfla_2400 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative long-chain fatty-acid CoA ligase; PFAM: AMP-binding enzyme.
 
 
0.718
ADU48486.1
AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873: IPR020845; KEGG: bcv:Bcav_1901 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative long chain fatty acid CoA ligase; PFAM: AMP-binding enzyme.
 
 
0.717
ADU47928.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: nml:Namu_4653 hypothetical protein; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative uncharacterized protein; PFAM: AMP-binding enzyme.
  
  
 
0.705
ADU46912.1
AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873: IPR020845; KEGG: rrs:RoseRS_0623 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
 
 
0.682
ADU47560.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR020845; KEGG: cmi:CMM_1418 long-chain-fatty-acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
  
  
 
0.651
acpP
Phosphopantetheine-binding protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.552
ADU46915.1
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: cai:Caci_4507 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.
 
 0.550
ADU46813.1
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090: IPR006089; KEGG: mgi:Mflv_5166 Fis family transcriptional regulator; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Transcriptional regulator, Fis family; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
  
 
 0.525
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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