close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU50026.1COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR020845; KEGG: gob:Gobs_4160 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative acyl-CoA synthetase, long-chain fatty acid:CoA ligase; PFAM: AMP-binding enzyme. (502 aa)    
Predicted Functional Partners:
ADU47580.1
COGs: COG1075 acetyltransferase and hydrolase with the alpha/beta hydrolase fold; InterPro IPR000073; KEGG: kfl:Kfla_1265 lipase class 2; PFAM: alpha/beta hydrolase fold; SPTR: Putative secreted lipase; PFAM: Putative serine esterase (DUF676).
     
  0.800
ADU47928.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: nml:Namu_4653 hypothetical protein; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative uncharacterized protein; PFAM: AMP-binding enzyme.
  
  
 
0.706
ADU48729.1
AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845: IPR018294: IPR000873; KEGG: kfl:Kfla_2400 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative long-chain fatty-acid CoA ligase; PFAM: AMP-binding enzyme.
 
 
0.704
ADU48486.1
AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873: IPR020845; KEGG: bcv:Bcav_1901 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative long chain fatty acid CoA ligase; PFAM: AMP-binding enzyme.
 
 
0.702
ADU46912.1
AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873: IPR020845; KEGG: rrs:RoseRS_0623 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
 
 
0.666
ADU46915.1
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: cai:Caci_4507 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.
 
 
 0.661
ADU47560.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR020845; KEGG: cmi:CMM_1418 long-chain-fatty-acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
  
  
 
0.651
ADU48425.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR001753: IPR006176: IPR006108; KEGG: tcu:Tcur_1759 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 
 0.596
rplF
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.581
ADU46813.1
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090: IPR006089; KEGG: mgi:Mflv_5166 Fis family transcriptional regulator; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Transcriptional regulator, Fis family; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
  
 
 0.561
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (28%) [HD]