STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU50046.1Nuclease (SNase domain-containing protein); COGs: COG1525 Micrococcal nuclease (thermonuclease) homologs; InterPro IPR006021: IPR002071; KEGG: kse:Ksed_15970 micrococcal nuclease-like nuclease; PFAM: nuclease (SNase domain-containing protein); SMART: nuclease (SNase domain-containing protein); SPTR: Micrococcal nuclease-like nuclease; PFAM: Staphylococcal nuclease homologue. (290 aa)    
Predicted Functional Partners:
ADU50124.1
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
    0.732
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.587
ADU48002.1
ATPase associated with various cellular activities AAA_5; COGs: COG1401 GTPase subunit of restriction endonuclease; InterPro IPR011704: IPR003593; KEGG: bfa:Bfae_05450 GTPase subunit of restriction endonuclease; PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; SPTR: ATPase family associated with various cellular activities (AAA), putative; PFAM: AAA domain (dynein-related subfamily).
  
   
 0.570
ADU50045.1
GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: sma:SAV_5596 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
       0.544
ilvA
Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
       0.506
ADU48090.1
COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: art:Arth_3190 acyltransferase 3; PFAM: acyltransferase 3; SPTR: Acyltransferase 3; PFAM: Acyltransferase family.
  
  
 0.452
ADU49770.1
COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: kse:Ksed_26820 predicted acyltransferase; PFAM: acyltransferase 3; SPTR: Predicted acyltransferase; manually curated; PFAM: Acyltransferase family.
  
  
 0.416
ADU48816.1
COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: bcv:Bcav_3022 acyltransferase 3; PFAM: acyltransferase 3; SPTR: Lipopolysaccharide modification acyltransferase; PFAM: Acyltransferase family.
  
  
 0.413
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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