STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ADU50046.1Nuclease (SNase domain-containing protein); COGs: COG1525 Micrococcal nuclease (thermonuclease) homologs; InterPro IPR006021: IPR002071; KEGG: kse:Ksed_15970 micrococcal nuclease-like nuclease; PFAM: nuclease (SNase domain-containing protein); SMART: nuclease (SNase domain-containing protein); SPTR: Micrococcal nuclease-like nuclease; PFAM: Staphylococcal nuclease homologue. (290 aa)    
Predicted Functional Partners:
ADU48002.1
ATPase associated with various cellular activities AAA_5; COGs: COG1401 GTPase subunit of restriction endonuclease; InterPro IPR011704: IPR003593; KEGG: bfa:Bfae_05450 GTPase subunit of restriction endonuclease; PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; SPTR: ATPase family associated with various cellular activities (AAA), putative; PFAM: AAA domain (dynein-related subfamily).
  
     0.566
ADU50045.1
GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: sma:SAV_5596 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
       0.544
ilvA
Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
       0.506
ADU48134.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.437
ADU48090.1
COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: art:Arth_3190 acyltransferase 3; PFAM: acyltransferase 3; SPTR: Acyltransferase 3; PFAM: Acyltransferase family.
  
  
 0.434
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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