STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU50061.1YhhN family protein; InterPro IPR012506; KEGG: xce:Xcel_1936 YhhN family protein; PFAM: YhhN family protein; SPTR: Putative uncharacterized protein; PFAM: YhhN-like protein. (219 aa)    
Predicted Functional Partners:
ADU47416.1
Peptidase S45 penicillin amidase; COGs: COG2366 Protein related to penicillin acylase; InterPro IPR002692: IPR014395: IPR002034; KEGG: cfl:Cfla_0835 peptidase S45 penicillin amidase; PFAM: peptidase S45 penicillin amidase; SPTR: Penicillin amidase; PFAM: Penicillin amidase.
  
     0.565
ADU50062.1
KEGG: nth:Nther_1572 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.537
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.449
ADU46738.1
KEGG: xce:Xcel_3194 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain.
  
     0.444
ADU49336.1
KEGG: bcv:Bcav_1591 glycoside hydrolase family 2 sugar binding; SPTR: Glycoside hydrolase family 2 sugar binding; PFAM: Protein of unknown function (DUF2804).
  
     0.415
ADU47980.1
InterPro IPR018357: IPR001451; KEGG: cfl:Cfla_0787 transferase hexapeptide repeat containing protein; SPTR: Transferase hexapeptide repeat containing protein.
  
     0.408
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.