STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU50069.1D-serine/D-alanine/glycine:proton symporter, AAT family; COGs: COG1113 Gamma-aminobutyrate permease and related permease; InterPro IPR002293: IPR004841: IPR004840; KEGG: rha:RHA1_ro02269 amino acid APC transporter; PFAM: amino acid permease-associated region; SPTR: D-serine/D-alanine/glycine transporter, APC family protein; PFAM: Amino acid permease; TC 2.A.3.1.7. (505 aa)    
Predicted Functional Partners:
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
   
  
 0.474
glnE
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
      
 0.461
ADU50070.1
ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: sro:Sros_8858 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter.
       0.456
ADU50071.1
ABC-2 type transporter; InterPro IPR013525: IPR000412; KEGG: kra:Krad_2016 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter; PFAM: ABC-2 type transporter; TIGRFAM: ABC transporter efflux protein, DrrB family.
       0.456
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
   
 0.437
ADU49753.1
SNARE associated Golgi protein-like protein; COGs: COG0586 membrane-associated protein; InterPro IPR015414; KEGG: nca:Noca_4353 DedA family membrane protein; PFAM: SNARE associated Golgi protein; SPTR: Conserved membrane protein (DedA family protein); manually curated; PFAM: SNARE associated Golgi protein.
  
     0.427
ADU50072.1
Transcriptional regulator, MerR family; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: kra:Krad_2015 putative transcriptional regulator, MerR family; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: Putative transcriptional regulator, MerR family; PFAM: MerR family regulatory protein.
     
 0.423
ADU49870.1
COGs: COG1301 Na+/H+-dicarboxylate symporter; InterPro IPR001991; KEGG: sro:Sros_3870 sodium:dicarboxylate symporter; PFAM: sodium:dicarboxylate symporter; SPTR: Putative sodium:dicarboxylate symporter; PFAM: Sodium:dicarboxylate symporter family; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
  
  
 0.422
ADU49891.1
COGs: COG1966 Carbon starvation protein predicted membrane protein; InterPro IPR003706; KEGG: ach:Achl_0831 carbon starvation protein CstA; PFAM: carbon starvation protein CstA; SPTR: Carbon starvation protein CstA; PFAM: Carbon starvation protein CstA.
  
     0.412
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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