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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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Score
ADU50076.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (609 aa)    
Predicted Functional Partners:
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 0.935
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
 0.927
ADU48756.1
DnaB domain protein helicase domain protein; COGs: COG0305 Replicative DNA helicase; InterPro IPR007694; KEGG: ttr:Tter_1028 DnaB domain protein helicase domain protein; PFAM: DnaB domain protein helicase domain protein; SPTR: DnaB domain protein helicase domain protein; PFAM: DnaB-like helicase C terminal domain.
     
  0.900
ADU49610.1
DNA primase catalytic core domain; COGs: COG0358 DNA primase; InterPro IPR002694: IPR013264; KEGG: fra:Francci3_1282 DNA primase; PFAM: DNA primase catalytic core domain; SPTR: DNA primase; PFAM: DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core.
  
 
 0.825
ADU47391.1
IstB domain protein ATP-binding protein; COGs: COG1484 DNA replication protein; InterPro IPR003593: IPR002611; KEGG: rha:RHA1_ro06914 insertion sequence ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: Probable insertion sequence ATP-binding protein; PFAM: IstB-like ATP binding protein.
  
 
 0.757
ADU47657.1
IstB domain protein ATP-binding protein; COGs: COG1484 DNA replication protein; InterPro IPR002611: IPR003593; KEGG: rha:RHA1_ro06914 insertion sequence ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: Probable insertion sequence ATP-binding protein; PFAM: IstB-like ATP binding protein.
  
 
 0.757
ADU49604.1
IstB transposition helper protein; COGs: COG1484 DNA replication protein; InterPro IPR003593: IPR002611; KEGG: mkm:Mkms_5620 IstB ATP binding domain-containing protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: IstB domain protein ATP-binding protein; PFAM: IstB-like ATP binding protein.
  
 
 0.757
ADU46564.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
   
 0.702
nusG
Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination.
 
  
 0.671
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
  
 0.665
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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