STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU50077.1Protein of unknown function DUF2277; COGs: COG5552 conserved hypothetical protein; InterPro IPR018735; KEGG: ach:Achl_3874 hypothetical protein; PFAM: Protein of unknown function DUF2277; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2277). (91 aa)    
Predicted Functional Partners:
ADU50001.1
COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR012309; KEGG: nml:Namu_0826 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: DNA ligase; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region.
  
     0.657
ADU50078.1
Metallophosphoesterase; COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: rha:RHA1_ro00901 phosphoesterase; PFAM: metallophosphoesterase; SPTR: Possible phosphoesterase; PFAM: Calcineurin-like phosphoesterase.
       0.627
ADU48409.1
DNA polymerase LigD, polymerase domain protein; COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR002755: IPR014145; KEGG: amd:AMED_4612 ATP-dependent DNA ligase; PFAM: DNA primase small subunit; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: Eukaryotic and archaeal DNA primase small subunit; TIGRFAM: DNA ligase D; DNA polymerase LigD, polymerase domain.
  
     0.576
ADU50000.1
COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR002755; KEGG: kse:Ksed_15620 DNA polymerase LigD, polymerase domain; PFAM: DNA primase small subunit; SPTR: DNA ligase; TIGRFAM: DNA polymerase LigD, polymerase domain.
  
     0.569
ADU49370.1
Activator of Hsp90 ATPase 1 family protein; COGs: COG3832 conserved hypothetical protein; InterPro IPR013538; KEGG: nml:Namu_5220 activator of HSP90 ATPase 1 family protein; PFAM: Activator of Hsp90 ATPase 1 family protein; SPTR: Activator of Hsp90 ATPase 1 family protein; PFAM: Activator of Hsp90 ATPase homolog 1-like protein.
 
     0.487
ADU50079.1
Hypothetical protein; InterPro IPR018201; KEGG: kfl:Kfla_0729 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Pregnancy-associated plasma protein-A.
       0.431
ADU46691.1
DNA-(apurinic or apyrimidinic site) lyase; COGs: COG0266 Formamidopyrimidine-DNA glycosylase; InterPro IPR012319: IPR015886: IPR000214; KEGG: sna:Snas_1400 DNA-formamidopyrimidine glycosylase; PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Putative formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain; TIGRFAM: formamidopyrimidine-DNA glycosylase (fpg); Belongs to the FPG family.
  
     0.401
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.