STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU50081.1MATE efflux family protein; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: pac:PPA2259 hypothetical protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: Conserved membrane protein, MatE domain; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: putative efflux protein, MATE family. (441 aa)    
Predicted Functional Partners:
ADU50080.1
DNA alkylation repair enzyme; InterPro IPR014825; KEGG: amd:AMED_6049 putative DNA alkylation repair enzyme; PFAM: DNA alkylation repair enzyme; SPTR: Putative uncharacterized protein; PFAM: DNA alkylation repair enzyme.
  
    0.796
ADU48180.1
COGs: COG0539 Ribosomal protein S1; InterPro IPR003029: IPR000110; KEGG: jde:Jden_1229 30S ribosomal protein S1; PFAM: RNA binding S1 domain protein; SPTR: 30S ribosomal protein S1; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
  
    0.750
ADU48197.1
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020832: IPR020830: IPR020831: IPR020828: IPR 020829: IPR006424; KEGG: kfl:Kfla_3261 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydroge [...]
  
  
 0.653
ADU48880.1
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR006424: IPR020830: IPR020828: IPR020829: IPR 020832; KEGG: aau:AAur_2411 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Gl [...]
  
  
 0.653
ADU49895.1
Ankyrin; InterPro IPR002110: IPR020683; KEGG: nda:Ndas_2707 ankyrin; PFAM: Ankyrin; SMART: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
    
 
 0.574
ADU48735.1
Protein of unknown function DUF448; COGs: COG2740 nucleic-acid-binding protein implicated in transcription termination; InterPro IPR007393; KEGG: nfa:nfa40675 hypothetical protein; PFAM: protein of unknown function DUF448; SPTR: Putative uncharacterized protein; manually curated; PFAM: Protein of unknown function (DUF448).
   
 
 0.570
ADU50079.1
Hypothetical protein; InterPro IPR018201; KEGG: kfl:Kfla_0729 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Pregnancy-associated plasma protein-A.
  
    0.528
ADU48989.1
COGs: COG3920 Signal transduction histidine kinase; InterProIPR005467: IPR003594: IPR004358: IPR013656: IPR 011495; KEGG: kra:Krad_3796 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Putative two-component system sensor kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transduction histidine kinase; PAS fold.
  
   
 0.515
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR002547: IPR005121: IPR004532: IPR005146: IPR 005147; KEGG: kra:Krad_3163 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spiroch [...]
     
 0.490
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.456
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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