Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU50105.1NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086: IPR020476: IPR020084; KEGG: kse:Ksed_26900 ADP-ribose pyrophosphatase; PFAM: NUDIX hydrolase; SPTR: Putative uncharacterized protein; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. (161 aa)    
Predicted Functional Partners:
ADU50106.1
KEGG: ske:Sked_37910 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.869
ADU50107.1
KEGG: cfl:Cfla_3716 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.693
ADU50104.1
Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterProIPR002646: IPR006674: IPR014065: IPR006675: IPR 003607; KEGG: kse:Ksed_26890 tRNA adenylyltransferase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Putative RNA nucleotidyltransferase; TIGRFAM: tRNA adenylyltransferase; metal dependent phophohydrolase; PFAM: HD domain; Poly A polymerase head domain; TIGRFAM: tRNA adenylyltransferase; uncharac [...]
 
     0.682
ADU50108.1
RNA polymerase, sigma subunit, ECF family; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: svi:Svir_39650 RNA polymerase, sigma subunit, ECF family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: Putative RNA polymerase ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.
       0.678
ADU49447.1
COGs: COG2062 Phosphohistidine phosphatase SixA; InterPro IPR000086: IPR013078: IPR020084; KEGG: kse:Ksed_03520 ADP-ribose pyrophosphatase; PFAM: NUDIX hydrolase; Phosphoglycerate mutase; SPTR: Putative uncharacterized protein; PFAM: NUDIX domain; Phosphoglycerate mutase family.
  
     0.515
ADU48986.1
Lipolytic protein G-D-S-L family; InterPro IPR001087; KEGG: kse:Ksed_18470 hypothetical protein; PFAM: lipolytic protein G-D-S-L family; SPTR: Putative uncharacterized protein; PFAM: GDSL-like Lipase/Acylhydrolase.
 
     0.501
ADU50109.1
KEGG: tfu:Tfu_3107 hypothetical protein; SPTR: RNA polymerase sigma-70 factor.
       0.453
ADU50110.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR013027: IPR000103: IPR005982: IPR008255; KEGG: kse:Ksed_26940 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
     
 0.437
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
    0.418
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.