Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU50110.1COGs: COG0492 Thioredoxin reductase; InterPro IPR013027: IPR000103: IPR005982: IPR008255; KEGG: kse:Ksed_26940 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. (342 aa)    
Predicted Functional Partners:
ADU50111.1
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR013766: IPR017936: IPR006662: IPR005746: IPR 017937; KEGG: tbi:Tbis_3579 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
 
 0.992
ADU48220.1
COGs: COG0520 Selenocysteine lyase; InterPro IPR000192: IPR010970; KEGG: nda:Ndas_2959 cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; SPTR: Cysteine desulphurases, SufS; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
 
 
  0.915
ADU49309.1
Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789: IPR000103: IPR013027; KEGG: rer:RER_40230 two-component system thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Response regulator receiver domain.
 
  
0.914
ADU49790.1
COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: nca:Noca_3943 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme.
   
 
 0.904
ADU46922.1
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR017936: IPR013766: IPR017937: IPR006662: IPR 005746; KEGG: nml:Namu_1297 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
 
 
 0.681
ADU47820.1
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR005746: IPR006662: IPR017937: IPR013766: IPR 017936; KEGG: ske:Sked_24970 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
 
 
 0.676
ADU48913.1
COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR017936; KEGG: bcv:Bcav_1333 thioredoxin domain protein; SPTR: Putative thioredoxin; PFAM: Thioredoxin.
  
 
 0.630
ADU50108.1
RNA polymerase, sigma subunit, ECF family; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: svi:Svir_39650 RNA polymerase, sigma subunit, ECF family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: Putative RNA polymerase ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.
     
 0.603
ADU50112.1
Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002477: IPR002508; KEGG: kfl:Kfla_7065 cell wall hydrolase/autolysin; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding domain 1 protein; SMART: cell wall hydrolase/autolysin; SPTR: Cell wall hydrolase/autolysin; PFAM: Putative peptidoglycan binding domain; N-acetylmuramoyl-L-alanine amidase.
  
    0.557
ADU50109.1
KEGG: tfu:Tfu_3107 hypothetical protein; SPTR: RNA polymerase sigma-70 factor.
       0.548
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.