Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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ADU50111.1Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR013766: IPR017936: IPR006662: IPR005746: IPR 017937; KEGG: tbi:Tbis_3579 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family. (107 aa)    
Predicted Functional Partners:
ADU50110.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR013027: IPR000103: IPR005982: IPR008255; KEGG: kse:Ksed_26940 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
 
 0.992
ADU49309.1
Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789: IPR000103: IPR013027; KEGG: rer:RER_40230 two-component system thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Response regulator receiver domain.
  
 
 0.847
ADU47957.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.738
ADU48782.1
COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027; KEGG: nml:Namu_0350 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
     
 0.650
ADU50112.1
Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002477: IPR002508; KEGG: kfl:Kfla_7065 cell wall hydrolase/autolysin; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding domain 1 protein; SMART: cell wall hydrolase/autolysin; SPTR: Cell wall hydrolase/autolysin; PFAM: Putative peptidoglycan binding domain; N-acetylmuramoyl-L-alanine amidase.
   
   0.642
ADU47212.1
COGs: COG1333 ResB protein required for cytochrome c biosynthesis; KEGG: kra:Krad_0630 ResB family protein; SPTR: Conserved protein, putative c-type cytochrome biogenesis protein; PFAM: ResB-like family.
      
 0.635
ADU48385.1
COGs: COG1333 ResB protein required for cytochrome c biosynthesis; KEGG: ahe:Arch_1471 ResB family protein; SPTR: ResB family protein; PFAM: ResB-like family.
      
 0.635
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.616
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.615
groL-2
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.608
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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