STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALC98502.1Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)    
Predicted Functional Partners:
ALC98501.1
Potassium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.967
ALC99311.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.745
ALC99089.1
Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.640
ALC99090.1
Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.618
ALD00618.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.580
ALC98503.1
Excisionase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.522
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.441
Your Current Organism:
Actinomyces
NCBI taxonomy Id: 712122
Other names: A. sp. oral taxon 414, Actinomyces sp. oral taxon 414
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.