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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALC99368.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)    
Predicted Functional Partners:
ALC99444.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.735
ALD00847.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.731
ALC99085.1
dUTPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.728
ALC98946.1
IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.727
ALC99120.1
Proteasome protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.668
ALD00718.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.644
ALC99122.1
Pup--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.632
ALC99405.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.632
ALC99575.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.623
ALC99812.1
Fructose-2,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.595
Your Current Organism:
Actinomyces
NCBI taxonomy Id: 712122
Other names: A. sp. oral taxon 414, Actinomyces sp. oral taxon 414
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