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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALC99556.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)    
Predicted Functional Partners:
ALC99555.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.687
ALD00719.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.639
ALD00592.1
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.532
ALC99702.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.511
ALC99700.1
Excisionase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.486
ALC99557.1
Osmotically inducible protein OsmC; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.480
ALC99111.1
DNA primase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.448
ALD00540.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.445
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.423
ALC99905.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.413
Your Current Organism:
Actinomyces
NCBI taxonomy Id: 712122
Other names: A. sp. oral taxon 414, Actinomyces sp. oral taxon 414
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