Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ANR70271.1Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (637 aa)    
Predicted Functional Partners:
ANR70270.1
Uptake hydrogenase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
ANR70276.1
Hydrogenase expression/formation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.981
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.972
ANR71572.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.970
ANR70272.1
Ni/Fe-hydrogenase, b-type cytochrome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.963
ANR70989.1
Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.869
AXF19_01590
Formate dehydrogenase; Frameshifted; too many ambiguous residues; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.838
ANR70275.1
Hydrogenase accessory protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.825
ANR70279.1
Hydrogenase formation protein HypD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.774
ANR70278.1
Hydrogenase assembly protein HypC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.767
Your Current Organism:
Selenomonas
NCBI taxonomy Id: 712528
Other names: S. sp. oral taxon 126, Selenomonas sp. oral taxon 126
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