Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (455 aa)    
Predicted Functional Partners:
ANR71547.1
Precorrin isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.994
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 0.990
ANR71545.1
Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.988
ANR71551.1
Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.986
ANR71552.1
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.985
ANR71550.1
Cobalamin biosynthesis protein CbiG; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.979
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.977
ANR71548.1
Precorrin-6x reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.973
ANR71553.1
Precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.968
Your Current Organism:
Selenomonas
NCBI taxonomy Id: 712528
Other names: S. sp. oral taxon 126, Selenomonas sp. oral taxon 126
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