Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (209 aa)    
Predicted Functional Partners:
ANR69725.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.996
ANR71559.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.862
ANR71560.1
ACT domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0237 family.
       0.843
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
 
  
 0.830
ANR71557.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family.
     
 0.817
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.761
AXF19_11595
Repressor LexA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.705
ANR71556.1
3-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.675
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
 
 0.664
ANR69779.1
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.616
Your Current Organism:
Selenomonas
NCBI taxonomy Id: 712528
Other names: S. sp. oral taxon 126, Selenomonas sp. oral taxon 126
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