Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
kdkA3-deoxy-D-manno-octulosonic acid kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. (249 aa)    
Predicted Functional Partners:
AHE97313.1
3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
   
 0.978
AHE97319.1
ADP-heptose--LPS heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.967
AHE97101.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.884
AHF00240.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.879
AHE97553.1
Cyclophilin; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.830
AHE97728.1
Deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.806
AHE97219.1
Molecular chaperone of HSP90 family; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.798
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity.
    
 0.798
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.778
AHE96931.1
CDP-6-deoxy-delta-3,4-glucoseen reductase; Catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.773
Your Current Organism:
Thioalkalivibrio paradoxus
NCBI taxonomy Id: 713585
Other names: T. paradoxus ARh 1, Thioalkalivibrio paradoxus ARh 1, Thioalkalivibrio paradoxus str. ARh 1, Thioalkalivibrio paradoxus strain ARh 1
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