close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHE98221.16-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)    
Predicted Functional Partners:
queE
7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
 
 0.984
folE
GTP cyclohydrolase; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.973
AHE98220.1
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.954
AHE98219.1
Trans-aconitate methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.953
AHE98222.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.917
AHE99167.1
6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
AHE98223.1
CDP-alcohol phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
     0.875
queC
7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
  
  
 0.861
AHE98524.1
Sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.786
AHE98216.1
FkbM family methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.768
Your Current Organism:
Thioalkalivibrio paradoxus
NCBI taxonomy Id: 713585
Other names: T. paradoxus ARh 1, Thioalkalivibrio paradoxus ARh 1, Thioalkalivibrio paradoxus str. ARh 1, Thioalkalivibrio paradoxus strain ARh 1
Server load: medium (54%) [HD]