STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
MetBCOG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (346 aa)    
Predicted Functional Partners:
RAM_41650
Cystathionine beta-synthase; COG0031 Cysteine synthase.
 
 0.989
MetH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.964
metH
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.964
CysK
COG0031 Cysteine synthase.
  
 0.951
MetY
COG2873 O-acetylhomoserine sulfhydrylase.
 
 
0.944
MetY-2
COG2873 O-acetylhomoserine sulfhydrylase.
 
 
0.942
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
  
 0.938
RAM_42585
Aminotransferase; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.
 
 
 0.938
NirA
COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.934
IlvE-2
COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
  
 0.931
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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