STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_00405NADH-flavin reductase; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. (216 aa)    
Predicted Functional Partners:
PrsA
Ribose-phosphate pyrophosphokinase; COG0462 Phosphoribosylpyrophosphate synthetase.
       0.779
RAM_00400
Hypothetical protein.
       0.694
PoxB
COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.
   
    0.604
PoxB-2
Pyruvate dehydrogenase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.
   
    0.604
PoxB-3
COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.
   
    0.604
RAM_27180
Integral membrane protein; COG0701 Predicted permeases.
  
    0.474
RAM_06725
Acetyltransferase; COG2388 Predicted acetyltransferase.
  
    0.445
RAM_37210
Hypothetical protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases.
  
     0.428
RAM_05630
COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
      
 0.420
RAM_07850
COG0513 Superfamily II DNA and RNA helicases.
      
 0.420
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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