STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmdGDPmannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (327 aa)    
Predicted Functional Partners:
AlgD
COG1004 Predicted UDP-glucose 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
 
 0.950
RAM_05170
Mannose-1-phosphate guanylyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).
    
 0.920
RAM_01055
Aminotransferase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.
  
 
 0.914
RAM_00590
Rossmann-fold NAD(P)(+)-binding protein; COG0500 SAM-dependent methyltransferases.
 
  
 0.886
WcaJ
Undecaprenyl-phosphate galactose phosphotransferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
 
  
 0.680
RfbP
COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
 
  
 0.658
GalE-5
UDP-glucose 4-epimerase; COG0451 Nucleoside-diphosphate-sugar epimerases.
 
 
 0.609
RAM_12195
Hypothetical protein.
  
  
 0.606
Ugd-2
COG1004 Predicted UDP-glucose 6-dehydrogenase.
 
  
 0.589
cysC
Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.
     
 0.585
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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