STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_00665Two-component system histidine kinase; COG3275 Putative regulator of cell autolysis. (441 aa)    
Predicted Functional Partners:
RAM_00680
COG3279 Response regulator of the LytR/AlgR family.
 
 
 0.918
RAM_08065
COG3279 Response regulator of the LytR/AlgR family.
 
 
 0.889
RAM_00685
Hypothetical protein.
 
     0.819
RAM_00690
COG4147 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.757
SohB
COG0616 Periplasmic serine proteases (ClpP class).
       0.743
RAM_08055
Transmembrane transport protein; COG4147 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.593
RAM_00655
Hypothetical protein.
 
     0.589
MutM
COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.
       0.542
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.