STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SohBCOG0616 Periplasmic serine proteases (ClpP class). (269 aa)    
Predicted Functional Partners:
RAM_00665
Two-component system histidine kinase; COG3275 Putative regulator of cell autolysis.
       0.784
nhaA
Na+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
      0.625
RAM_00655
Hypothetical protein.
 
     0.606
RAM_29635
Hypothetical protein; COG0457 FOG: TPR repeat.
  
  
 0.565
RAM_00700
Hypothetical protein.
 
     0.493
RAM_05595
COG3428 Predicted membrane protein.
 
    0.492
RAM_35865
Hypothetical protein; COG1796 DNA polymerase IV (family X).
       0.482
nnrD
Ribokinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NA [...]
       0.481
MoaB
Molybdenum cofactor biosynthesis protein B; COG0521 Molybdopterin biosynthesis enzymes.
       0.478
RAM_00675
Endo-1,3-beta-glucanase; COG2273 Beta-glucanase/Beta-glucan synthetase.
       0.475
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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