STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HmgACOG3508 Homogentisate 1,2-dioxygenase. (390 aa)    
Predicted Functional Partners:
RAM_41590
COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.
 
 0.997
RAM_22210
4-hydroxyphenylpyruvate dioxygenase; COG1082 Sugar phosphate isomerases/epimerases.
  
 0.974
RAM_15120
Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
 
  
 0.958
RAM_00800
Hypothetical protein; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.
 
     0.728
RAM_25920
Hydroxylase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
 
  
 0.652
RAM_14665
Hypothetical protein.
  
 
 0.646
RAM_18075
Hypothetical protein.
  
 
 0.646
RAM_27435
Hypothetical protein.
  
 
 0.646
RAM_27440
Hypothetical protein.
  
 
 0.646
PhhB
COG2154 Pterin-4a-carbinolamine dehydratase.
  
  
 0.636
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.