STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YaeRGlyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases. (144 aa)    
Predicted Functional Partners:
RAM_01250
Patatin-like phospholipase; COG1752 Predicted esterase of the alpha-beta hydrolase superfamily.
 
     0.614
RAM_17835
LuxR family transcriptional regulator fused with ATPase domain; COG2771 DNA-binding HTH domain-containing proteins.
  
     0.554
RAM_28815
LuxR family transcriptional regulator fused with ATPase domain; COG3899 Predicted ATPase.
 
     0.539
RAM_08675
Hypothetical protein.
 
   
 0.525
RAM_28810
LuxR family transcriptional regulator fused with ATPase domain; COG3899 Predicted ATPase.
  
     0.525
RAM_28605
Hypothetical protein.
  
     0.489
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.469
RAM_24250
COG0236 Acyl carrier protein.
 
  
 0.463
GltA
COG0372 Citrate synthase.
  
  
 0.458
RAM_45635
Ketosteroid isomerase-like protein; COG4319 Ketosteroid isomerase homolog.
 
    0.426
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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