STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_01465COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). (138 aa)    
Predicted Functional Partners:
SigB
COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.
 
 
 0.929
RAM_18340
COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
 
 0.837
RAM_20890
Fused protein kinase and phosphatase containing multi-sensor domain; COG2202 FOG: PAS/PAC domain.
 
 
 0.768
SigB-2
COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.
 
 
 0.711
SpoI
COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
 
 0.700
RAM_25120
Hypothetical protein.
  
     0.677
RAM_16275
COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).
 
 
 0.646
SigB-3
COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.
 
 
 0.631
RAM_37015
Hypothetical protein.
  
     0.630
fbiC
FO synthase; COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
  
    0.613
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.