STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SpoICOG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family. (117 aa)    
Predicted Functional Partners:
RAM_20890
Fused protein kinase and phosphatase containing multi-sensor domain; COG2202 FOG: PAS/PAC domain.
 
 
 0.832
RAM_30220
Two-component system sensor kinase; COG2202 FOG: PAS/PAC domain.
  
 
 0.817
RAM_00900
Hypothetical protein.
  
     0.687
RAM_01465
COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase).
 
 
 0.680
RAM_01455
COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase).
 
 
 0.620
RAM_01480
Integral membrane protein; COG1988 Predicted membrane-bound metal-dependent hydrolases.
       0.609
SigB
COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.
 
 
 0.603
RAM_21360
Phosphatase.
 
 
 0.556
RAM_33605
Phosphatase; COG2208 Serine phosphatase RsbU, regulator of sigma subunit.
 
 
 0.530
RAM_15540
Phosphatase; COG2208 Serine phosphatase RsbU, regulator of sigma subunit.
 
 
 0.516
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.