STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AesLipase; COG0657 Esterase/lipase. (320 aa)    
Predicted Functional Partners:
RAM_28280
Esterase/lipase-like protein; COG0657 Esterase/lipase.
  
     0.772
RAM_18760
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.723
RAM_18765
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.723
RAM_27510
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.723
NuoF-2
COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
    
   0.707
BglX-2
COG1472 Beta-glucosidase-related glycosidases.
     
 0.617
RAM_01595
COG1846 Transcriptional regulators.
       0.531
RAM_01605
Esterase/lipase-like protein; COG0627 Predicted esterase.
       0.480
RAM_20005
Polyketide synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
 
 0.464
RAM_01590
Hypothetical protein.
       0.457
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.