STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_01985COG2233 Xanthine/uracil permeases. (443 aa)    
Predicted Functional Partners:
pyrR
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
  
  
 0.937
pyrB
COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.937
carA
COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family.
  
  
 0.892
PyrF
COG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.883
AllB
L-hydantoinase/allantoinase; COG0044 Dihydroorotase and related cyclic amidohydrolases.
 
  
 0.833
pyrD
Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
  
 0.788
RAM_13970
Integral membrane protein.
  
  
 0.761
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.753
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.748
RAM_34095
Phenylhydantoinase; COG0044 Dihydroorotase and related cyclic amidohydrolases.
  
  
 0.748
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.