STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_02455Molybdopterin binding domain-containing oxidoreductase; COG2041 Sulfite oxidase and related enzymes. (518 aa)    
Predicted Functional Partners:
RAM_02450
COG0526 Thiol-disulfide isomerase and thioredoxins.
  
    0.579
FadD
COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
    0.528
rex
Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
 
     0.515
QcrC
COG2010 Cytochrome c, mono- and diheme variants.
   
 
 0.467
RAM_09775
COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
  
   0.462
RAM_15020
Hypothetical protein.
 
     0.435
RAM_33580
Hypothetical protein; COG3707 Response regulator with putative antiterminator output domain.
  
    0.425
RAM_21370
Two-component system response regulator; COG2203 FOG: GAF domain.
  
    0.421
MoaB
Molybdenum cofactor biosynthesis protein B; COG0521 Molybdopterin biosynthesis enzymes.
 
   
 0.416
RAM_28000
Two-component system response regulator; COG2203 FOG: GAF domain.
  
    0.409
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.