STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
RAM_02545Cytochrome C biogenesis protein; COG0526 Thiol-disulfide isomerase and thioredoxins. (188 aa)    
Predicted Functional Partners:
RAM_02540
COG0406 Fructose-2,6-bisphosphatase.
  
 
 0.969
hemL
COG0001 Glutamate-1-semialdehyde aminotransferase.
  
  
 0.939
CcdA
COG0785 Cytochrome c biogenesis protein.
 
  
 0.912
ResB
COG1333 ResB protein required for cytochrome c biosynthesis.
 
  
 0.880
RAM_02560
Cytochrome C assembly membrane protein; COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component.
  
  
 0.872
msrA
Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 
 0.809
hemE
uroporphyrinogen-III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.777
CoxB
COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2.
 
 
 
 0.746
HemL
COG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.745
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
     
 0.725
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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