STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RAM_02560Cytochrome C assembly membrane protein; COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component. (322 aa)    
Predicted Functional Partners:
ResB
COG1333 ResB protein required for cytochrome c biosynthesis.
 
  
 0.992
CcdA
COG0785 Cytochrome c biogenesis protein.
 
  
 0.986
HemD
uroporphyrin-III C-methyltransferase HemD; COG0007 Uroporphyrinogen-III methylase.
 
  
 0.880
RAM_02545
Cytochrome C biogenesis protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
  
 0.872
RAM_47440
COG1131 ABC-type multidrug transport system, ATPase component.
  
 
 0.844
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.718
CysG
uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain).
  
  
 0.710
RAM_02565
Hypothetical protein.
  
    0.688
HemB
COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.641
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.633
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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